Identification of risk factors and biomarkers for liver diseases, hepatocellular carcinoma, cholangiocarcinoma and gallbladder carcinoma. The ESCALON stduy.

Recruiting

• Conditions: Hepatobiliary cancers; liver- gallbladder and bileduct cancers; 10017990; 10019815

• Registration Number: NL-OMON48295
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 1950

Inclusion Criteria

HPB related malignancies, • Age >= 18 years of age
• Diagnosed with HCC, CCA or GBC
• Written informed consent, HPB related diseases, • Age >= 18 years of age
• Diagnosed with viral hepatitis, cirrhosis, PSC, NAFLD or gallstones
• Written informed consent, Healthy controls, • Age >= 18 years of age
• No signs of relevant disease
• Written informed consent

Exclusion Criteria

For all groups, • Females who are pregnant or breast-feeding.
• History or other evidence of severe illness, other malignancy or any other
condition which would make the patient, in the opinion of the investigators,
unsuitable for the study.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Identification of specific biomarkers for diagnosis and risk-prediction of HCC,<br /><br>GBC or CCA.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>