[18F]-FHBG for PET imaging of herpes viruses: a control study with healthy volunteers

Completed

• Conditions: psychiatric disorder; schizophrenia; 10039628

• Registration Number: NL-OMON35582
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 8

Inclusion Criteria

-Age above 18
-Written informed consent for participation

Exclusion Criteria

-Pregnancy, or presumption of pregnancy
-The use of anticoagulants or having coagulation disorder
-Use of any investigational drug
-Use of somatic medication which may affect the immune system
-Current or recent (<1 year) alcohol or substance abuse
-Current psychiatric disorder or a first degree family member with a major psychiatric disorder
-Current systemic disease
-Current infection with a herpes virus
-Major metabolic disease
-Somatic, organic or neurological disorder
-Participation in a scientific research study (<1 year) involving radiation

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the metabolic rate of [18F]-FHBG in the brain.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are the results of the PANSS, 15-word test, CPT and<br /><br>the antibodies against herpes viruses.</p><br>