Evaluation of Transient Dyspnea During Gadoxetic Acid Enhanced Multiphasic Liver MRI
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Number of Participants With Transient Dyspnea.
研究概览
简要总结
The purpose of this study is to observe transient dyspnea pattern after Gd-EOB-DTPA administration by obtaining continuous dynamic T1 weighted image data.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are referred to MR unit for hepatocyte-specific contrast enhanced liver MRI using gadoxetic acid, to characterize focal liver lesion or to investigate diffuse liver disease
- •OR, Liver living donor candidates
- •AND subjects who sign the informed consent.
排除标准
- •Minors under 18 years old
- •All contraindication to MRI
- •Hypersensitivity to Gd
- •Biliary obstruction
研究组 & 干预措施
Observe1
Patients who are referred to MR unit for hepatocyte-specific contrast (gadoxetic acid) enhanced liver magnetic resonance imaging (MRI)
干预措施: gadoxetic acid (Drug)
Observe1
Patients who are referred to MR unit for hepatocyte-specific contrast (gadoxetic acid) enhanced liver magnetic resonance imaging (MRI)
干预措施: Magnetic resonance imaging (MRI) (Other)
结局指标
主要结局
Number of Participants With Transient Dyspnea.
时间窗: during 3 minutes after contrast media administration
A sudden onset irregular breathing pattern after EOB administration, based on MRI k-space data (not participants' symptom). The k-space data was analyzed after the enrollment completion.
次要结局
- Duration of Transient Dyspnea in Participants With Transient Dyspnea.(during 3 minutes after contrast media administration)
研究者
Jeong Min Lee
MD
Seoul National University Hospital