NCT00519259Unknown1 期
Tolerability, Safety, and Pharmacokinetics of Repeated Sublingual Doses of Lobeline
适应症
相关药物
试验速览
- 阶段
- 1 期
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Tolerability
研究概览
简要总结
The purpose of this study is to assess safety and pharmacokinetics of sublingual lobeline in healthy normal volunteers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Must be able to provide written informed consent
- •Must have a body mass index between 18 and 30
- •Have no medical contraindications as determined by medical history, physical exam, ECG, hematology and blood chemistry profile, and urinalysis
- •Must have a negative drug test at screening and admission
- •If female of child bearing potential, must agree to use birth control
排除标准
- •Please contact the site for more information
结局指标
主要结局
Tolerability
次要结局
- Safety
- Pharmacokinetic parameters
- Cardiovascular responses
- Psychological effects of lobeline
研究者
研究点 (2)
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