Clinical Efficacy and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride to Arrest Incipient Carious Lesions in Permanent Molar Teeth With or Without Application of LED Light: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 366
- 主要终点
- Caries arrest
研究概览
简要总结
The study aims to compare the effect of international brand ammonia based 38% SDF, water based silver fluoride solution (AgF), an aqueous silver fluoride solution, and local brand ammonia based SDF with and without LED light application on caries arrest of initial enamel pits and fissure caries for permanent teeth of young adults
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •high caries risk dental students
- •Males or females
- •Medically free
- •Not taking medication
- •At least had one active carious tooth
- •Posterior permanent teeth
排除标准
- •non-Egyptian students
- •Lack of compliance
- •Allergic reaction to the materials used
- •Pregnancy
- •Dental students cannot give consent
- •Teeth that will be extracted for orthodontic reasons
- •Dental fluorosis
- •Hypo calcified teeth
- •Systemic diseases affecting teeth, such as amelogenesis imperfecta
- •Severe periodontal affection
研究组 & 干预措施
Pits and fissures receive International Silver Diamine Fluoride for caries arrest
Remineralization and prevention of incipient pits and fissure caries of permanent molars by International Silver Diamine Fluoride application for 60 seconds
干预措施: International Sliver Diamine Fluoride (Other)
Pits and fissures receive Local brand Egyptian Sliver Diamine Fluoride for caries arrest
Remineralization and prevention of incipient pits and fissure caries of permanent molars by local brand Egyptian Silver Diamine Fluoride application for 60 seconds
干预措施: Local brand Egyptian Silver Diamine Fluoride (Other)
Pits and fissures receive Sliver Fluoride for caries arrest
Remineralization and prevention of incipient pits and fissure caries of permanent molars by Silver Fluoride application for 60 seconds
干预措施: Silver Fluoride (Other)
Pits and fissures receive International Silver Diamine Fluoride with LED for caries arrest
Remineralization and prevention of incipient pits and fissure caries of permanent molars by Silver Diamine Fluoride application for 10 seconds, followed by the application LED light for 20 seconds
干预措施: International Sliver Diamine Fluoride with LED light (Other)
Pits and fissures receive local brand Egyptian Silver Diamine Fluoride with LED for caries arrest
Remineralization and prevention of incipient pits and fissure caries of permanent molars by local brand Egyptian Silver Diamine Fluoride application for 10 seconds, followed by LED light for 20 seconds
干预措施: Local brand Egyptian Silver Diamine Fluoride with LED light (Other)
Pits and fissures receive Sliver Fluoride with LED for caries arrest
Remineralization and prevention of incipient pits and fissure caries of permanent molars by Silver Fluoride application for 10 seconds, followed by application of LED light for 20 seconds
干预措施: Silver Fluoride with LED light (Other)
结局指标
主要结局
Caries arrest
时间窗: After 3, 6, and 12 months.
Lesion activity will be assessed by caries status (active/inactive) using visual and tactile inspection for surface discontinuities and texture. The participants will be examined under unit light using a 0.5 mm ball-ended (CPI) probe and a dental mirror. The teeth will be cleaned and dried by a water-air spray syringe before the examination.
次要结局
未报告次要终点
研究者
Alaa Amr Khodair
Lecturer Assistant
Cairo University