Faecal Incontinence in Prostate Cancer Survivors Treated With Moderately Hypofractionated Radiotherapy
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- faecal incontinence after prostate radiation therapy
研究概览
简要总结
The objective of the study is to determine the incidence of faecal incontinence in prostate cancer survivors treated with moderately hypofractionated radiation therapy and correlate the dose received by the anal sphincter with the degree of faecal incontinence.
详细描述
The investigators know that high doses of irradiation in the anal sphincter are associated with more chronic fecal leaks in survivors irradiated by normofractionated radiotherapy prostate cancer.
The safe dose of irradiation of the anal sphincter with radiotherapy modern techniques (volumetric modulated arc therapy with moderately hypofracctionation) is unknown.
Urgency and faecal incontinence greatly affects the quality of life of these patients.
Therefore, it is interesting to implement strategies to protect the anatomical structures involved in fecal continence.
The objective of the study is to determine the incidence of faecal incontinence in prostate cancer survivors treated with modern moderately hypofractionated radiation therapy and correlate the dose received by the anal sphincter with the degree of faecal incontinence.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Prostate cancer survivors treated in our department by hypofractionated radiotherapy
排除标准
- •Relapse of prostate cancer
- •Other active cancer
- •Mental disorder
结局指标
主要结局
faecal incontinence after prostate radiation therapy
时间窗: change 5 years after completion of radiotherapy
grade of faecal incontinence in prostate cancer survivors
次要结局
- Quality of life after prostate radiation therapy(5 years after completion of radiotherapy)
研究者
Joan Lozano Galan
Principal investigator
Consorci Sanitari de Terrassa