Randomised comparative study between atomised intranasal dexmedetomidine , lignocaine and ketamine as premedication for flexible fibreoptic bronchoscopy

the study aims to compare the effectiveness of  atomised intranasal demedetomedine, lignocaine and ketamine as premedication for flexible fibreoptic bronchoscopy. Primary objective is to evaluate the incidence of moderate to severe cough during the procedure. Secondary objective is to compare the patient satisfaction score, endoscopist satisfaction score, ramsay sedation score and if any rescue lignocaine required. ASA I & II patients of more than 18 years age with BMI less than 30 kg/m2 will be included and patients with history of bronchial asthma or allergy to the study drugs will be excluded. 60 patients will be randomly divided into 3 groups of 20 each. atomised ketamine (2mg/kg), atomised dexmedetomidine (2 mcg/kg) and atomised lignocaine (1.5 mg/kg) will be given as premedication 30 inutes prior to the procedure and the above mentioned objectives will be assessed. P values less than 0.05 will be considered significant.