Genetic Study of Transcription Factor 7 Like 2 (TCF7L2) Gene Polymorphism in Type 2 Diabetes Mellitus
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 164
- 试验地点
- 1
- 主要终点
- TO identify the individual risk of TCF7L2 gene mutation in patients with type 2 diabetes mellitus.
研究概览
简要总结
THIS STUDY IS A CASE-CONTROL STUDY OF TRANSCRIPTION FACTOR 7-LIKE 2 (TCF7L2) GENE POLYMORPHISM IN HOSPITAL PATIENTS WITH TYPE 2 DIABETES MELLITUS. IT WILL BE CONDUCTED IN BLDE (DEEMED TO BE UNIVERSITY) SHRI B.M. PATIL MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTRE, VIJAYAPURA. TOTAL OF 164 PEOPLE (82 PATIENTS AND 82 HEALTHY CONTROLS) WILL BE TAKEN INTO THIS STUDY AFTER APPLYING THE INCLUSION AND EXCLUSION CRITERIA. THE PRIMARY OUTCOME OF THE STUDY IS TO DETECT THE RISK OF THE TCF7L2 GENEPOLYMORPHISM IN PATIENTS WITH TYPE 2 DIABETES MELLITUS. THE SECONDARY OUTCOME OF THE STUDY WILL BE HELPFUL TO THE DEVELOPMENT OF BIOMARKERS FOR THE CLINICIAN AND THE COMMUNITY. BY USING THE STUDY’S AGGREGATED DATA FOR THE EARLY DETECTION OF THOSE AT RISK FOR TYPE 2 DIABETES MELLITUS AND EARLY INTERVENTION, THE BURDEN OF DISEASE IN TERMS OF MORBIDITY AND MORTALITY OF DISEASE WILL BE REDUCED.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 35.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients Admitted/ Attending OPD with Type 2 Diabetes Mellitus.
排除标准
- •Patients with Type 1 Diabetes Mellitus.
- •Patients with Thyroid Disorders.
- •Patients with Gestational Diabetes.
结局指标
主要结局
TO identify the individual risk of TCF7L2 gene mutation in patients with type 2 diabetes mellitus.
时间窗: 12 months
次要结局
- This study will be helpful for the development of biomarkers for clinicians & the community. By using the study’s aggregated data for early detection of type 2 diabetes mellitus & early intervention, the burden of disease in terms of morbidity & mortality of disease will be reduced.(12 month)
研究者
Dr. Sankranthi Rajasekhar
BLDE Deemed to be University Shri B M Patil Medical College, Hospital and Research Centre