Effects of pioglitazone on abdominal fat and reactive oxygen species in type 2 diabetes mellitus
Not Applicable
- Conditions
- Type 2 diabetes mellitus
- Registration Number
- JPRN-C000000441
- Lead Sponsor
- Second Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, Diabetes and Life-style related disease center, Tomishiro Chuo Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
- History of cerebro- and cardio-vascular disease - History of congestive heart failure - History of ketoacidosis or diabetic coma - Moderate to severe liver dysfunction - Moderate to severe renal dysfunction - Moderate to severe infection, before and after operation, severe trauma - Contraindication to antidiabetic medication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Abdominal fat mass - ROS (reactive oxygen species) - Blood lipid parameters
- Secondary Outcome Measures
Name Time Method - Glycemic control (OGTT, HbA1c) - Cardiac function - Aortic stiffness (Pulse wave velocity)