Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis
Phase 3
Completed
- Conditions
- Post-operative Endophthalmitis
- Interventions
- Procedure: Intravitreal injection of antibioticsProcedure: Intravitreal injection of Betamethasone + antibiotics
- Registration Number
- NCT01768078
- Lead Sponsor
- Centre Hospitalier Universitaire Dijon
- Brief Summary
One useful effect of early intravitreal corticotherapy is to diminish inflammatory complications after endophthalmitis, which may cause, at least in part, serious complications (retinal detachment, macular edema) which are, more than the infection, causes of the complications seen after acute endophthalmitis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 112
Inclusion Criteria
- All patients male or female with no age limit
- Hospitalized for the diagnosis and treatment of acute endophthalmitis following cataract surgery
- Who had given their consent after being informed about intravitreal corticotherapy
Exclusion Criteria
- Patients who refused or were unable to give their consent
- Prior intravitreal corticotherapy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description without corticoids Intravitreal injection of antibiotics - with corticoids Intravitreal injection of Betamethasone + antibiotics -
- Primary Outcome Measures
Name Time Method Measure the evolution of visual acuity up to12 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (6)
CHU de Besançon
🇫🇷Besançon, France
CHU de Saint Etienne
🇫🇷Saint Etienne, France
CHU de Strasbourg
🇫🇷Strasbourg, France
CHU
🇫🇷Dijon, France
CHU de Grenoble
🇫🇷Grenoble, France
CHU de Nancy
🇫🇷Nancy, France