Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis

Phase 3

Completed

• Conditions: Post-operative Endophthalmitis

• Registration Number: NCT01768078
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

One useful effect of early intravitreal corticotherapy is to diminish inflammatory complications after endophthalmitis, which may cause, at least in part, serious complications (retinal detachment, macular edema) which are, more than the infection, causes of the complications seen after acute endophthalmitis.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-09
• Study First Submitted: 2013-01-08
• Study First Submitted QC: 2013-01-14
• Study First Posted: 2013-01-15
• Primary Completion: 2014-10
• Study Completion: 2014-10
• Status Verified: 2018-12
• Last Update Submitted: 2018-12-26
• Last Update Posted: 2018-12-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 112

Inclusion Criteria

• All patients male or female with no age limit
• Hospitalized for the diagnosis and treatment of acute endophthalmitis following cataract surgery
• Who had given their consent after being informed about intravitreal corticotherapy

Exclusion Criteria

• Patients who refused or were unable to give their consent
• Prior intravitreal corticotherapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Measure the evolution of visual acuity	up to12 months

Trial Locations

Locations (6)

CHU de Besançon; 🇫🇷 Besançon, France

CHU; 🇫🇷 Dijon, France

CHU de Grenoble; 🇫🇷 Grenoble, France

CHU de Nancy; 🇫🇷 Nancy, France

CHU de Saint Etienne; 🇫🇷 Saint Etienne, France

CHU de Strasbourg; 🇫🇷 Strasbourg, France