Cooperative Research Centre (CRC) for Alertness, Safety and Productivity: Respiratory Phenotyping for Obstructive Sleep Apnoea – Main study

Recruiting

• Conditions: Obstructive Sleep Apnoea; Respiratory - Sleep apnoea

• Registration Number: ACTRN12615000918527
• Lead Sponsor: A/Prof Peter Catcheside

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-09-02
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

Diagnosis of obstructive sleep apnea
- Recommended usual care with CPAP treatment by their treating physician

Exclusion Criteria

- A history of significant COPD (Gold criteria 3-4), chronic ventilatory failure from any other cause or psychiatric disorders likely to place the patient at higher than normal risk or likely to confound experimental treatment outcomes.
- Physician recommended exclusion
- Patient unable (e.g. language difficulties) or unwilling to consent
- Central sleep apnea (central apnea index >5 /hr)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Apnoea-Hypopnoea Index (AHI) scored without conventional oxygen desaturation criteria [AHI assessed without standard desaturation criteria will be measured from each overnight polysomnography study (baseline night, single night of O2 treatment alone, single night of air (control) treatment) and compared between nights.]