IRCT2016020526377N1
Completed
Phase 2
Clinical trial to evaluate the role of radioprotection effect of curcumin in peripheral blood lymphocytes of patients with differentiated thyroid carcinoma treated with Iodine-131, by micronucleus assay
Vice Chancellor for Research, Shahid Beheshti University of Medical Sciences0 sites20 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- differentiated thyroid carcinoma(DTC).
- Sponsor
- Vice Chancellor for Research, Shahid Beheshti University of Medical Sciences
- Enrollment
- 20
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patients with differentiated thyroid cancer (follicular, papillary or mixed type) don't received destroying dose (ablative dose) of radioiodine up to now; no palpable neck mass; thyroid pathology reported there is no invasion to capsular and lymph areas and blood vessels; body scan with 131\-I don’t show any functional tissue in regions other than the thyroid bed; thyroid cancer confirmed by biopsy; all patients have total thyroidectomy; TSH level before administration of radioiodine is higher than 30 IU/ML.
- •exclusion criteria: after treatment with 131 I if there is abnormal tissue absorption of iodine in other areas of the thyroid bed; if patients after taking the first capsule of curcumin had a headache and dizziness; patient will be excluded.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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