Effect of Photobiomodulation and Enamel-Derived Matrix Proteins on Bone Repair in Maxillary Sinuses grafted with Deproteinized Bovine Bone

Not Applicable

Recruiting

• Conditions: Maxillary Sinus; C07.793.870

• Registration Number: RBR-10nyxwkr
• Lead Sponsor: niversidade Federal de Uberlândia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-10-19
• Last Update Posted: 23 January 2024
• Study Completion: 2027-12-30

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

The patient required to present between 18 and 60 years old. need unilateral or bilateral elevation of the floor of the maxillary sinus for subsequent installation of osseointegrated implants. present bone availability associated with the alveolar ridge adjacent to the maxillary sinus less than or equal to 3mm. present good systemic health. present at least less than 4 months of healing of the socket after tooth extraction

Exclusion Criteria

Smokers. decompensated diabetics. patients with chronic or aggressive periodontitis. patients who use drugs that alter bone metabolism. patients who have chronic infections of the upper airways. patients who chronically use anti-inflammatory drugs and antibiotics. people with bruxism. alcoholics. drug addicts. pregnant women or who wish to become pregnant in the next year. history of radiotherapy treatment in the head and neck region. patients with pathologies that affect bone metabolism. patients who have had a major disruption of the sinus membrane during surgery

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The application of dual-wavelength laser therapy and enamel matrix-derived protein will increase bone formation by 15% in maxillary sinuses grafted with deproteinized bovine bone compared to the isolated use of this graft.

Secondary Outcome Measures

Name	Time	Method
The application of dual-wavelength laser therapy and protein derived from the enamel matrix will increase the volume of mineralized tissues in maxillary sinuses grafted with deproteinized bovine bone by 10% compared to the isolated use of this graft.;Implants placed in areas of maxillary sinuses grafted with deproteinized bovine bone treated with dual-wavelength laser therapy and with protein derived from the enamel matrix will have a success rate 10% higher than in areas grafted with deproteinized bovine bone in adjunctive treatment