The Effect of Laparoscopic Sleeve Gastrectomy on the Change in Carotid Intima-media Thickness in Patients With Obesity: Prospective Randomized Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- carotid intima-media thickness
研究概览
简要总结
The aim of this study was to compare carotid intima-media thicknesses in laparoscopic sleeve gastrectomy patients preoperatively and at the end of the first postoperative year.
详细描述
Obesity is not only a disease in itself, but also predisposes to many other diseases. Cardiac diseases are one of the systems that obesity predisposes to. Obesity has been found to increase the risk of cardiac disease by increasing carotid intima-media thickness in patients with obesity. Surgery is known to be the most effective treatment for obesity and laparoscopic sleeve gastrectomy is the most common bariatric surgery procedure. Laparoscopic sleeve gastrectomy may reduce the risk of cardiac disease by reducing carotid intima-media thickness in patients with obesity through effective weight loss.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 years old,
- •BMI > 35 kg/m2
- •Laparoscopic sleeve gastrectomy will be performed
- •patients with cardiac disease
排除标准
- •patients without cardiac disease
- •patients who performed other bariatric surgery procedures
研究组 & 干预措施
laparoscopic sleeve gastrectomy
laparoscopic sleeve gastrectomy
干预措施: surgery (Other)
结局指标
主要结局
carotid intima-media thickness
时间窗: From enrollment to the end of the first year after laparoscopic sleeve gastrectomy
The primary outcome of the study was to compare carotid intima-media thickness at the end of the first postoperative year after laparoscopic sleeve gastrectomy (LSG) with baseline carotid intima-media thickness in patients with obesity. The investigators will measure carotid intima-media thickness with carotid doppler ultrasound before LSG and at the end of the first year after LSG and compare the results.
次要结局
未报告次要终点
研究者
Muhammed Taha Demirpolat
Clinical Professor
Umraniye Education and Research Hospital