CTRI/2017/12/010891已完成未知
A Comparison of Efficacy of Isotretinoin with that of Methotrexate in Moderate to Severe Chronic Plaque Psoriasis
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- one
- 入组人数
- 43
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Patients having >10% of body surface area involved by psoriasis and no psoriatic arthritis.
- •2.Patients having moderate-to-severe chronic plaque psoriasis (defined by a score of at least 6 on the Psoriasis Area-and-Severity Index (PASI).
- •3.Patients not on any form of systemic antipsoriatic treatment for at least 4 weeks and/or topical treatment for at least 2 weeks prior to the initiation of therapy.
排除标准
- •1.Patients less than 18 years of age.
- •2.Pregnant and / or lactating females.
- •3.Patients noncompliant with an effective regimen of contraception.
- •4.Patients having hepatic or renal impairment, deranged lipid profile, hematologic impairment, any acute infection requiring antimicrobial therapy, uncontrolled hypertension or diabetes mellitus, with BMI >30 or known psychiatric illness.
- •5.Patients having a history of cancer, including skin cancer or hematologic, cerebral or pulmonary neoplasia.
- •6.Patients who were alcoholic or had a long history of alcohol intake.
研究者
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