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临床试验/NL-OMON55380
NL-OMON55380招募中不适用

Amyloid pathology in cognitively normal elderly subjects - PreclinAD

Vrije Universiteit Medisch Centrum0 个研究点目标入组 200 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
200

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • - Age 60-100 years - Monozygotic twin - Telephone Interview for Cognitive
  • Status modified (TICSm) >22 - Geriatric Depression Scale (GDS) (15 item) <11 -
  • Consortium to Establish a Registry for Alzheimer*s Disease (CERAD) 10 word list
  • immediate and delayed recall (> -1.5 SD of age adjusted normative data) -
  • Clinical Dementia Rating (CDR) scale of 0 with a score on the memory subdomain

排除标准

  • - clinical diagnosis of probable Alzheimer's disease or mild cognitive
  • - neurological problems like Parkinson's disease, Huntington disease, severe
  • head trauma, braintumour, stroke with physical impairment, epilepsy currently
  • using antiepileptic drugs, braininfection
  • - known uncontrolled diabetes, thyroid disease, vitamin B12 deficiency
  • - psychiatric disorder like psychosis or schizophrenia

研究者

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