Topical TRANeXamic acid in total Knee replacement
- Conditions
- Osteoarthritis of the kneeMusculoskeletal DiseasesGonarthrosis [arthrosis of knee]
- Registration Number
- ISRCTN68578366
- Lead Sponsor
- niversity Hospital of North Tees and Hartlepool (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 150
Undergoing unilateral primary cemented total knee replacement
1. Undergoing unilateral primary total knee replacement for trauma or tumour
2. Allergic to tranexamic acid
3. Bleeding tendency (e.g. Haemophilic and platelets disorders)
4. Warfarin, treatment dose of low molecular weight heparin (LMWH) or conventional heparin
5. History of deep vein thrombosis (DVT) and pulmonary embolism
6. Renal failure with creatinine > 250 micromole/l
7. Female subjects of child bearing potential must have a negative pregnancy test
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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