The Effect of Docosahexaenoic Acid Supplementation on Biomarkers of Concussion Over the Course of a Year in Canadian National Rugby Players

Not Applicable

Completed

• Conditions: Head Trauma
• Interventions: Dietary Supplement: Docosahexaenoic Acid (DHA)

• Registration Number: NCT03582267
• Lead Sponsor: Texas Christian University

Brief Summary

Nutrition interventions may present a safe and relatively risk free intervention for protection against subconcussive impacts. Docosahexaenoic acid (DHA, 22:6n-3) is the principal Omega 3 polyunsaturated fatty acid in the brain, playing an integral role in the brain's development and structural integrity. The goal of this study is to determine if supplementation with DHA attenuates blood biomarkers of repetitive head trauma linked to sub-concussive impacts sustained in rugby participation.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-08-01
• Study First Submitted: 2018-06-27
• Study First Submitted QC: 2018-07-09
• Study First Posted: 2018-07-10
• Primary Completion: 2018-08-01
• Study Completion: 2019-08-01
• Status Verified: 2019-09
• Last Update Submitted: 2019-09-12
• Last Update Posted: 2019-09-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Canadian national rugby athletes on 7s and 15s teams

Exclusion Criteria

• None

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Dietary Supplement	Docosahexaenoic Acid (DHA)	Docosahexaenoic Acid (DHA)

Primary Outcome Measures

Name	Time	Method
Blood concentration of neurofilament light protein	12 times throughout course of 1 year	Concentrations of neuronally derived proteins measured in blood

Trial Locations

Locations (1)

Texas Christian Universti; 🇺🇸 Fort Worth, Texas, United States