The Effect of Docosahexaenoic Acid Supplementation on Biomarkers of Concussion Over the Course of a Year in Canadian National Rugby Players
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Blood concentration of neurofilament light protein
研究概览
简要总结
Nutrition interventions may present a safe and relatively risk free intervention for protection against subconcussive impacts. Docosahexaenoic acid (DHA, 22:6n-3) is the principal Omega 3 polyunsaturated fatty acid in the brain, playing an integral role in the brain's development and structural integrity. The goal of this study is to determine if supplementation with DHA attenuates blood biomarkers of repetitive head trauma linked to sub-concussive impacts sustained in rugby participation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Canadian national rugby athletes on 7s and 15s teams
排除标准
- 未提供
研究组 & 干预措施
Dietary Supplement
Docosahexaenoic Acid (DHA)
干预措施: Docosahexaenoic Acid (DHA) (Dietary Supplement)
No Intervention
No Docosahexaenoic Acid supplementation
结局指标
主要结局
Blood concentration of neurofilament light protein
时间窗: 12 times throughout course of 1 year
Concentrations of neuronally derived proteins measured in blood
次要结局
未报告次要终点
研究者
Jonathan Oliver
Assistant Professor
Texas Christian University