DRKS00011383
Recruiting
Not Applicable
Autoimmune-Lymphproliferative Primary Immunodeficiencies: A clinical, immunological and genetic cohort study (AL-PID study, formerly: ALPS study) - AL-PID (formerly: ALPS)
niversitätsklinikum FreiburgCentrum für Chronische Immundefizienz (CCI)0 sites600 target enrollmentDecember 21, 2016
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Autoimmune Lymphoproliferative Syndrome other genetically defined or up to now not yet defined primary immunodeficiencies
- Sponsor
- niversitätsklinikum FreiburgCentrum für Chronische Immundefizienz (CCI)
- Enrollment
- 600
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Chronic benign lymphoproliferation (i.e. splenomegaly \+/\- lymphadenopathy at 2 sites without infectious or malignant cause)
- •2\.Autoimmune disease (i.e. AI cytopenia OR inflammatory bowel disease OR CNS inflammatory disease OR interstitial lung disease)
- •one of the two above manifestions
- •3\.At least one factor indicating a primary immunodeficiency (i.e. infection susceptibility OR additional autoimmune or inflammatory manifestations OR hypogammaglobulinemia OR aberrant immunophenotype OR positive family history OR consanguinity)
Exclusion Criteria
- •No written informed consent of patient or parents (in case of minors) has been obtained
Outcomes
Primary Outcomes
Not specified
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