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A study on the use of a hydrogel during breast conserving surgery to improve precision of targeting and positioning of breast irradiation.

Recruiting
Conditions
breast cancer, irradiation, hydrogel, target definition, positioning, <br />mammacarcinoom, bestraling, hydrogel, doeldefinitie, positionering
Registration Number
NL-OMON28313
Lead Sponsor
Erasmus MC- Cancer Institute
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

•Woman

•Undergoing breast conserving surgery

Exclusion Criteria

•Oncoplasty technique (level 2 Oncoplastic breast surgery) planned

•Node positive (pre-operatively diagnosed)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
the Conformity Index (Cx) of target definition.
Secondary Outcome Measures
NameTimeMethod
the distance between observers’ target volumes (dCOM), target volumes, Cavity Visualisation Score, feasibility of the hydrogel marker instillation, stability of the hydrogel marker volume over time, adverse events, ease of use, motion of hydrogel marker/clips over time, the feasibility of patient positioning based on the hydrogel marker on cone beam computed tomography (CBCT) and planar kV images and the accuracy of this procedure compared to positioning based on the surgical clips.
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