NCT02861547Unknown不适用
Development and Validation of a Prognostic Score for Early Death in Head Injury Patients in the Traumatic Brain Injury Intensive Care Unit of Dijon CHU
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 355
- 试验地点
- 1
- 主要终点
- Early death
研究概览
简要总结
Traumatic brain injury (TBI) is a serious condition with high morbidity and mortality. The Glasgow score alone, assessed at the initial phase, is not enough to determine the prognosis.
The aim of this study is to define and to evaluate a prognostic score for early death based on clinical and CT-scan findings in an observational retrospective derivation cohort of patients hospitalized for traumatic brain injury.
This cohort will allow us to carry out a uni- and then multi-variate analysis so as to create a prognostic score for early death.
We will subsequently test this score in a prospective validation cohort.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Traumatic brain injury (PMSI code (Programme Médicalisation des Systèmes d'Information) S 06.70 and S 06.71) Age>14 years Surviving more than 6h after the trauma Hospitalized in the traumatic brain injury intensive care unit and managed in accordance with international guidelines Who underwent a cerebral CT-scan
排除标准
- •Ongoing treatment with anticoagulants or antiplatelets Pregnant women Persons without national health insurance cover Children less than 15 years old Under guardianship.
结局指标
主要结局
Early death
时间窗: Through the study completion up to 2 years
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
TBI-Prognosis Multicenter Prospective StudyTraumatic Brain InjuryNCT02452541CHU de Quebec-Universite Laval315
已完成
不适用
S100 Protein in Minor/Mild Traumatic Brain InjuryMinor/Mild Traumatic Brain InjuryNCT00822445Assistance Publique - Hôpitaux de Paris500
招募中
不适用
The Research for New Clinical Diagnostic Strategy of Specific Biomarkers for Traumatic Brain InjuryTraumatic Brain InjuryNCT03976492Baiyun Liu450
已完成
不适用
A Prospective Outcome Study in Patients With Moderate to Severe Traumatic Brain InjuryBrain Injuries, TraumaticBrain Injury Traumatic ModerateBrain Injury Traumatic SevereNCT03810222FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS225
已完成
不适用
Blood Biomarkers to Improve Management of Children With Traumatic Brain InjuryTraumatic Brain InjuryNCT05413499Nantes University Hospital1,570