Predictive Value of the DD4 Questionnaire on Depressive Relapse After Hospitalization

Recruiting

• Conditions: Depressive Episode

• Registration Number: NCT05678907
• Lead Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche

Brief Summary

This is a prospective, longitudinal, single-center observational study of data from the medical records of patients hospitalized after a characterized depressive episode and reviewed three months after hospital discharge, as part of a normally scheduled evaluation.

Detailed Description

Patients in the study were hospitalized following a characterized depressive episode. The study is based on a review of these patients' medical records and data from the three-month assessment. No additional assessments are planned.

Study Timeline

• Study First Submitted: 2022-12-22
• Study First Submitted QC: 2022-12-22
• Study Start: 2023-01-02
• Study First Posted: 2023-01-10
• Status Verified: 2024-06
• Last Update Submitted: 2024-06-28
• Last Update Posted: 2024-07-01
• Primary Completion: 2025-02-28
• Study Completion: 2025-02-28

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Patient 18 years of age or older, having been informed of the research
• Patient hospitalized at the Auzon Clinic for a characterized depressive episodé (isolated episode or recurrent depressive disorder)
• Discharged from hospitalization
• Considered in remission (total or partial) and with a MADRS score < 20

Exclusion Criteria

• Patient hospitalized for < 15 days
• Patient with bipolar depression
• Patient with a psychotic disorder
• Patient using narcotics with a "moderate to severe" severity
• Patient previously included in this study
• Patient under court protection, guardianship or curatorship
• Patient unablé to respond correctly to a depression self-assessment questionnaire

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Depressive episode relapse	Month 3	Relapse within three months of hospitalization

Secondary Outcome Measures

Name	Time	Method
Depressive symptomology	Month 3	Measured with the Montgomery and Asberg (MADRS) scale
Psychic symptoms of depression	Month 3	The Multidimensional Self-Questionnaire for Depression Assessment DD4 (Ducher's Depression Scale) is presented in the form of four modules.; Each module consists of 15 identical questions (I feel sad, I suffer morally...).; The formulation of the questions allows for evaluation from 0 to 4 in different dimensions: DD4 A: Global Evaluation (not at all true, a little true, rather true, very true, completely true) DD4 F: Frequency Evaluation (never, sometimes, often, very often, permanently) DD4 I: Intensity Evaluation (not at all, slightly, fairly, a lot, enormously) DD4 M: Maximal Evaluation (uses the criteria of the global evaluation, but during the moments when the patient feels the saddest or most depressed). An additional question asks about the frequency of these periods (never, sometimes, often, very often, permanently).

Trial Locations

Locations (1)

Clinique de l'Auzon; 🇫🇷 La Roche-Blanche, France