Pulmonary Rehabilitation: Effects on Cognitive Functioning, Mood, Anxiety, and Quality of Life in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease COPD
- Sponsor
- Tilburg University
- Enrollment
- 261
- Locations
- 1
- Primary Endpoint
- Change in Mood and Anxiety
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this project is to investigate whether a 12-week, fulltime pulmonary rehabilitation program can enhance cognitive functioning, mood, anxiety, and quality of life in patients with Chronic Obstructive Pulmonary Disease (COPD).
Investigators
Margriet M. Sitskoorn
Professor, PhD
Tilburg University
Eligibility Criteria
Inclusion Criteria
- •Referral to the Extensive Pulmonary Rehabilitation Program
Exclusion Criteria
- •Unfinished primary school
- •Referral to the Compact Pulmonary Rehabilitation Program
Outcomes
Primary Outcomes
Change in Mood and Anxiety
Time Frame: In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks.
Hospital Anxiety and Depression Scale (HADS) Symptom Checklist 90 - Revised (SCL-90-R), subscales Anxiety, Depression, Agoraphobia
Change in Quality of Life
Time Frame: In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks.
Saint George Respiratory Questionnaire (SGRQ) SF-36 Health Survey
Change in 6 Minute Walking distance Test(6-MWT)
Time Frame: In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks.
6 Minute Walking distance Test (6-MWT)
Change in Objective Cognitive functioning
Time Frame: In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks.
CNS-Vital Signs, computerized neuropsychological assessment WMS - Verbal Paired Associates Direct Recall Word fluency-category (GIT): animals \& profession Letter fluency: D-A-T Purdue Pegboard
Change in Subjective Cognitive Functioning
Time Frame: In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks.
Cognitive Failures Questionnaire (CFQ)
Secondary Outcomes
- Dropout from pulmonary rehabilitation(From the moment of randomization untill the moment of dropout from pulmonary rehabilitation, assessed up to 1 year after randomization.)
- Adherence to pulmonary rehabilitation(These data are collected during the total period of pulmonary rehabilitation, which has a time frame of 12 weeks.)
- Change in Fatigue(In the experimental group, this measure is assessed in the first and last week of rehabilitation with an average time frame of 11 weeks. In the Control group, this measure is assessed before and after waiting time with an average time frame of 5 weeks.)