The Effect of Cancer Treatments on Speech Perception in Noise, Cognition, and Quality of Life

Turku University Hospital0 个研究点目标入组 250 人开始时间: 2024年4月14日最近更新: 2024年8月21日

适应症

试验速览

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•Age 18-75, Diagnosis of a cancer that will be treated with a curative intent with either cisplatin, oxaliplatin, cisplatin-based chemoradiation therapy of the head and neck region or radiation therapy of the head and neck region (subjects in the treatment groups), Age-normative hearing (according to the ISO standard 7029:2017), Ability to provide written informed consent, Native Finnish speaker

•Inability to provide written informed consent, Current or prior major otological condition that has affected or had the potential to affect hearing, Conductive hearing loss or asymmetric hearing loss of any severity, Severe sensorineural hearing loss, Prior malignancy that has been treated with chemotherapeutics and/or radiation therapy, Prior use of ototoxic medication, Any condition that, in the opinion of the investigator, would interfere with adherence to study requirements, Pregnancy, breast-feeding, or aim of becoming pregnant during the study, Allergy or hypersensitivity to study medications or their ingredients

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