The use of lasers with antimicrobial drugs to treat infected wounds in people with diabetes: randomized clinical trial
- Conditions
- Diabetes mellitusWounds and injuriesE10-E14
- Registration Number
- RBR-23p4zr
- Lead Sponsor
- Maria Girlane Sousa Albuquerque Brandão
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Individuals aged 18 years or over; being diabetic and presenting an infected wound (evaluation of the wound will be carried out by analyzing clinical signs: presence of odor, exudate, discoloration of the tissues inside and margins of the wound, edema, friable and hemorrhagic granulation tissue); attend the clinic on pre-established days.
Suspected or confirmed pregnancy; use immunosuppressive drugs; being on antibiotics or having finished treatment less than 30 days; use of any topical medication on the wound for less than seven days; diagnosis / Treatment of Carcinoma; presenting a wound with an area greater than 144 cm2; anemia (Hb less than 12 g / dL); Chronic Kidney Failure; osteomyelitis; being under the influence of alcohol or psychotropic substances; chronic malnutrition; peripheral vascular insufficiency.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method It is expected to find a reduction in the infectious infiltrate, through the use of methylene blue laser therapy, using the microbiological analysis of the lesion. We will observe throughout the treatment, the microbiological load before, during and after the treatment.<br>
- Secondary Outcome Measures
Name Time Method It is expected to find a reduction in the lesion area, through the use of methylene blue laser therapy, using the analysis of the process in tissue repair using the PUSH scale. We will observe throughout the treatment, the reduction of the lesion area, exudate and granulation tissue, before, during and after the treatment.