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A randomised phase II trial of personalized peptide vaccination plus "Keppuchikuoto" vs personalized peptide vaccination alone for non small cell lung cancer patients

Phase 2
Completed
Conditions
nresectable non smaii cell lung cancer
Registration Number
JPRN-UMIN000015173
Lead Sponsor
Kurume Unversity Cancer Vaccine Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

The following patients must be excluded: 1) Patients with severe underlying diseases / conditions(active and severe infectious diseases, circulatory diseases, respiratory diseases, renal diseases, immunodeficiencies, disturbance of coagulation, et al. Respiratory diseases are pulmonary damage, such as interstitial pneumonia and pneumoconiosis). 2) Active double cancer(synchronous double cancer and metachronous double cancer within 5 disease-free years), excluding carcinoma in situ(lesions equal to intraepithelial or intramucosal cancer) judged to have been cured with local treatment. 3) Patients with the past history of severe allergic reactions. 4) (Females)Pregnant or nursing patients. Patients desiring future fertility. (Males)Patients who do not sccept contraception from the 1st vaccination until 70 days after the last vaccination. 5) Patients who has taken Keppuchikuoto. 6) Patients who has taken Bevacizumab.(Participation is made possible when four or more weeks have passed from the last medication to an examination opening day.) 7) Patients who are judged inappropriate for entry to this clinical trial by doctors.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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