A phase III study comparing carboplatin plus pemetrexed followed by maintenance pemetrexed with docetaxel in elderly patients with advanced non-squamous non-small-cell lung cancer (JCOG1210/WJOG7813L CBDCA/PEM vs DOC Phase III)
Phase 3
- Conditions
- Elderly patients with advanced non-squamous non-small-cell lung cancer
- Registration Number
- JPRN-UMIN000011460
- Lead Sponsor
- Japan Clinical Oncology Group (JCOG)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 430
Inclusion Criteria
Not provided
Exclusion Criteria
1) Synchronous or metachronous active double malignancies 2) Infectious disease requiring systemic treatment 3) Fever of 38 degrees centigrade or higher 4) Psychotic disorder 5) Receiving systemic treatment of steroid or immunosuppressant 6) Uncontrolled diabetes mellitus treated with insulin 7) Uncontrolled hypertension 8) Unstable angina or myocardial infarction within the past 6 months 9) Positive for HBs antigen 10) Interstitial pneumonitis or lung fibrosis identified by chest CT 11) A past hypersensitive for polysorbate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survival
- Secondary Outcome Measures
Name Time Method Progression-free survival, response rate, symptom score, toxicity