Efficacy of rTMS in the Treatment of Patients With Migraine

Not Applicable

• Conditions: Migraine

• Registration Number: NCT00316979
• Lead Sponsor: Taipei Veterans General Hospital, Taiwan

Brief Summary

Migraine is a condition thought to be related to cortical hyperexcitability. Repetitive transcranial magnetic stimulation (rTMS) can modulate the cortical excitability by means of long-term potentiation or long-term depression. This study will will test the safety and efficacy of rTMS in the treatment of patients with Migraine.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-04
• Study First Submitted: 2006-04-20
• Study First Submitted QC: 2006-04-20
• Study First Posted: 2006-04-21
• Status Verified: 2010-06
• Last Update Submitted: 2010-06-06
• Last Update Posted: 2010-06-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Age of 18-65 years
• Diagnosed as migraine (with or without aura)
• More than 4 attacks per month for at least 3 months prior to study
• No preventive medication used
• Must be able to sign permit

Exclusion Criteria

• History of seizure or family history of seizures
• Women in pregnancy or breast-feeding
• Patient with medication overuse
• Patient with other medical, psychologic, or surgical illness
• Patient under preventive medications
• Prior rTMS examination one month within

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Reduction in days of migraine attack per month

Secondary Outcome Measures

Name	Time	Method
The reduction in dosage of acute abortive medication
The reduction of headache index

Trial Locations

Locations (1)

Headache Center, Teipei Veterans General Hospital; 🇨🇳 Taipei, Taiwan