Effect of Rosuvastatin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome : Assessment by frequencey domain optical coherence tomography study - Effect of lipid decrease treatment on plaque composition in patients with acute coronary syndrome(ACS)

Yamaguchi University Graduate School of Medicine Department of Medicine and Clinical Science0 个研究点目标入组 20 人开始时间: 2013年9月11日最近更新: 2023年10月17日

适应症

试验速览

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•1) Patient who needs lipid-lowering therapy other than research medicine during study period. 2)Patients with homozygous familial hypercholesterolemia,secondary hypercholesterolemia. 3) Patients with serum triglyceride > 400 mg/dL 4) Patient who has previous history of hypersensitivity for Statin. 5) Patients with hepatic function disorder (AST/ALT>= 100 IU/L, total bilirubin > 2.5mg/dL) 6) Patients with renal function disorder (serum creatinine >= 2.0mg/dL or creatinine clearance < 30mL/min/1.73m2) 7) Patients with serum CK > 500 IU/L 8) Patients receiving cyclosporine. 9) Pregnant women and women suspected of being pregnant. 10) Patients with hypothyroidism, hereditary muscular diseases (muscular dystrophy, etc.) or familial history of these diseases. 11)Patients with history of drug-related muscular disorder. 12) Patients with drug abuse or alcoholism. 13) Patient who has received treatment with medicines other than research medicine. Though using the medicine together other than the research medicine are enabled during this study period.The usage and the dosage are assumed to be no change during this study period. Statin other than research medicine, fibrate, cholesterol transporter inhibitor, and cyclosporines

发起方

Yamaguchi University Graduate School of Medicine Department of Medicine and Clinical Science