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Clinical Trials/NCT05196633
NCT05196633
Completed
Not Applicable

Effectiveness of Radial Extracorporeal Shock Wave Therapy and Visual Feedback Balance Training on Lower Limb Post-Stroke Spasticity, Trunk Performance and Balance: A Randomized Controlled Trial

Carol Davila University of Medicine and Pharmacy1 site in 1 country23 target enrollmentJanuary 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke, Ischemic
Sponsor
Carol Davila University of Medicine and Pharmacy
Enrollment
23
Locations
1
Primary Endpoint
Spasticity grade change
Status
Completed
Last Updated
last year

Overview

Brief Summary

This study assess the relationship between lower limb spasticity and trunk movements during static and dynamic balance in post-stroke patients who also underwent conventional physical therapy, visual feedback balance training and radial extracorporeal shock wave therapy intervention.

Detailed Description

The stabilometric assessment through Prokin system complemented the clinical evaluation and provided a more objective, global insight into the combined therapeutic effect. The stabilometric computerized system is both an assessment tool and a training system for static, dynamic balance and trunk. To date, it was used in various clinical trials as a training tool for promoting stance and balance improvement in several neurorehabilitation programs. Additional outcomes focused on the effectiveness on pain intensity, clonus, passive range of motion, lower limb sensorimotor function, and functionality. The adverse events were also attentively monitored during the trial.

Registry
clinicaltrials.gov
Start Date
January 1, 2021
End Date
August 31, 2021
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Carol Davila University of Medicine and Pharmacy
Responsible Party
Principal Investigator
Principal Investigator

Emanuela Elena Mihai

Principal Investigator

Carol Davila University of Medicine and Pharmacy

Eligibility Criteria

Inclusion Criteria

  • a hemorrhagic or ischemic stroke in acute, subacute or chronic phase;
  • no history of previous stroke;
  • lower limb post-stroke spasticity and spasticity grade ≥1 on the Modified Ashworth Scale (MAS);
  • pain intensity measured on Visual Analogue Scale (VAS) ≥1;
  • ability to stand unassisted in upright position for 30 seconds;
  • no change in anti-spastic drug dose or treatment and no changes in analgesic medication, as it could affect the results on the Modified Ashworth Scale and the Visual Analogue Scale
  • adult patients (\>18 years old)

Exclusion Criteria

  • other neurological and orthopaedic disorders or lower limb deformities that could in-terfere with motor performance and balance;
  • myopathies;
  • severe cognitive impairment, severe aphasia or inability to understand instructions;
  • severe spasticity;
  • visual field conditions or hemineglect;
  • patients unable to undergo follow-up evaluation and excluded from the final analysis;
  • anticoagulant medication or any contraindication to receive radial extracorporeal shockwave therapy (rESWT), or any contraindication to physical therapy.

Outcomes

Primary Outcomes

Spasticity grade change

Time Frame: Change from baseline Modified Ashworth Scale at 14 days

The Modified Ashworth Scale (MAS)

Secondary Outcomes

  • Pain intensity change(Change from baseline Visual Analogue Scale at 14 days)
  • Range of motion change(Change from baseline Passive Range of Motion at 14 days)
  • Stabilometric outcomes change(Change from baseline Prokin system parameters at 14 days)

Study Sites (1)

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