Influence of Thoracic Outlet Syndrome Severity on Upper Extremity Function and Neural Integrity

Completed

• Conditions: Thoracic Outlet Syndrome
• Interventions: Other: No intervention

• Registration Number: NCT05934734
• Lead Sponsor: Ahram Canadian University

Brief Summary

The purpose of this study is to investigate the relationship between the severity of thoracic outlet syndrome and upper extremity function, as well as neural integrity.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-06-28
• Study Start: 2023-06-30
• Study First Submitted QC: 2023-07-05
• Study First Posted: 2023-07-07
• Primary Completion: 2024-05-16
• Study Completion: 2024-05-16
• Status Verified: 2024-06
• Last Update Submitted: 2024-06-01
• Last Update Posted: 2024-06-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 136

Inclusion Criteria

• Age 18-65 years
• Diagnosed with thoracic outlet syndrome
• Willing and able to provide informed consent

Exclusion Criteria

• History of upper extremity surgery unrelated to thoracic outlet syndrome
• Other upper extremity disorders unrelated to thoracic outlet syndrome

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Cohort 2 (Moderate)	No intervention	Participants with moderate self-reported thoracic outlet syndrome symptoms (visual analog scale score 4-6). No intervention will be provided.
Cohort 1 (Mild)	No intervention	Participants with mild self-reported thoracic outlet syndrome symptoms (visual analog scale score 1-3).
Cohort 4 (Very Severe)	No intervention	Participants with very severe self-reported thoracic outlet syndrome symptoms (visual analog scale score 10). No intervention will be provided.
Cohort 3 (Severe)	No intervention	participants with severe self-reported thoracic outlet syndrome symptoms (visual analog scale score 7-9). No intervention will be provided

Primary Outcome Measures

Name	Time	Method
Isometric Muscle Strength of shoulder	Baseline	Maximum voluntary isometric strength of shoulder muscles will be measured using a handheld dynamometer.
Isometric Muscle Strength of elbow	Baseline	Maximum voluntary isometric strength of elbow muscles will be measured using a handheld dynamometer.
Nerve Conduction Studies of ulnar nerve	Baseline	Nerve conduction studies will assess the function/integrity of the ulnar nerve.
Isometric Muscle Strength of wrist	Baseline	Maximum voluntary isometric strength of wrist muscles will be measured using a handheld dynamometer.
Range of Motion (ROM) of the Shoulder joint	Baseline	Active and passive ROM will be measured using a standard goniometer.
Range of Motion (ROM) of the Elbow joint	Baseline	Active and passive ROM will be measured using a standard goniometer.
Range of Motion (ROM) of the Wrist joint	Baseline	Active and passive ROM will be measured using a standard goniometer.
Self-reported upper extremity function	Baseline	The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire, developed by the Institute for Work and Health, is used to measure patient-reported functional outcomes. The DASH questionnaire consists of 30 questions regarding limitations to complete physical activities due to upper extremity pain/impairment. Participants will be asked to respond to each question based on their experiences over the preceding week according to a 5-point Likert scale ranging from 1 (no difficulty) to 5 (unable to do). Responses will be scored out of 5 and averaged to produce a score out of 100 with higher scores representing greater disability.

Trial Locations

Locations (1)

Outpatient clinic of faculty of physical therapy, Ahram Canadian University; 🇪🇬 Al Ḩayy Ath Thāmin, Giza, Egypt