KCT0001891招募中未知
Modified LOw dose Cytarabine versus Hypomethylating agent in Elderly AML patients who are unfit for intensive chemotherapy: Randomized clinical study
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 65(Year) 至 o Limit（—）
- 性别
- All
入选标准
- •Patients with 65 years or older and unfit for intensive chemotherapy
- •(Satisfying at least 1 condition below)
- •- Poor-risk molecular cytogenetics group
- •- At least 2 conditions among followings (75 years old or older, ECOG (Eastern Cooperative Oncology Group) performance score 2-4, leukocyte counts at diagnosis > 50,000/microL)
- •- HCT-CI (Hematopoietic cell transplantation - comorbidity index) score with 3 or more
- •Sufficient liver or renal function (= 2.5 x upper normal limit)
排除标准
- •Acute promyelocytic leukemia presenting t(15;17) or PML/RARa
- •Central nervous system involvement
- •Myeloid sarcoma without bone marrow involvement
- •Uncontrolled prior infectious disease
- •Uncontrolled bleeding
- •Remnant previous malignancies in another organ
- •Serious cardiovascular disease within 6 months from screening
研究者
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