NCT01673399已完成4 期
Oxytocin Antagonist in Patients With Repeated Failure of Implantation. A Prospective Randomized Placebo-controlled Double-blind Study.
AZ Jan Palfijn Gent1 个研究点 分布在 1 个国家目标入组 138 人开始时间: 2012年2月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 138
- 试验地点
- 1
- 主要终点
- implantation rate
研究概览
简要总结
In this study the investigators compare the usual way of embryo transfer (without medication) with an embryo transfer while administering oxytocine antagonist. This to improve implantation and increase the pregnancy rate.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 38 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •IVF/ ICSI patients below 38 years
- •2e to 6e IVF-cycle
排除标准
- •patients with endocrinological diseases or problems
研究组 & 干预措施
Atosiban
Active Comparator
Patients receive a bolus injection of 6.75mg atosiban and following an atosibaninfusion at 18mg/u during 3 hours.
干预措施: Atosiban (Drug)
placebo
Placebo Comparator
Patients receive a placebo bolus injection (NaCl 0.9%)and an infusion of NaCl 0.9% during 3 hours
干预措施: placebo (Drug)
结局指标
主要结局
implantation rate
时间窗: 16 days from eggretrieval
the number of patients that show a positive serum blood pregnancy test
次要结局
- pregnancy rate(12 weeks)
研究者
Dr. Decleer Wim
gynecologist
AZ Jan Palfijn Gent
研究点 (1)
Loading locations...
相似试验
已完成
不适用
A Randomized Study on Comparing the Efficacy of Foley Catheter and Extraamniotic Saline Infusion for Labor InductionCervical RipeningLabor, InducedNCT00366951Rush University Medical Center200
已完成
3 期
A study to observe the effect of a drug Atosiban in patients undergoing embryo transfer procedure for in vitro fertilizatioCTRI/2017/09/009593Infertility Department200
尚未招募
不适用
Oxytocin in Multiparous WomenPregnancy RelatedNCT06372522Rambam Health Care Campus166
已完成
不适用
The Effect of Initiating Intravenous Oxytocin Infusion before Uterine Incision on Blood Loss During Elective Caesarean Section: A Randomized Clinical TrialPost partum haemorrhage preventionPACTR202111830813291wigboji Ndukwe Wilson180
招募中
4 期
Oxytocin Bolus Versus Infusion in Elective Cesarean Section"Elective Cesarean SectionNCT05236985Stony Brook University120