A Multicentre Randomised Controlled Trial of Culturally Adapted CBT Based Self Help Manual for Depression in Pakistan
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Depression
- Sponsor
- Pakistan Association of Cognitive Therapists
- Enrollment
- 192
- Primary Endpoint
- Hospital Anxiety and depression Rating Scale- Depression subscale
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
While CBT (Cognitive Behaviour Therapy)has been found to be effective in treating depression in West, only limited amount of research has been conducted to find assess its effectiveness in low and middle income countries. We have developed culturally sensitive CBT during the last few years in Pakistan. Pakistan has high rates of depression. And there is currently a need to develop and test evidence based treatments which are culturally sensitive and cost effective. IN this project we will be assessing the effectiveness of a culturally sensitive CBT based self help intervention for depression in Pakistan against care as usual, using a randomized controlled design.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All those who fulfil the diagnosis of Depressive episode (F32) or Recurrent depressive disorder (F33 except 33.4 ) using ICD10 RDC (International Classification of Diseases, Research Diagnostic Criteria), scored 8 or more on HADS (Hospital Anxiety and Depression Scale) Depression Sub-scale, are between the ages of 18-60 and either patient or the carer has at least 5 years of education.
Exclusion Criteria
- •The exclusion criteria include; excessive use of alcohol or drugs (using ICD 10 RDC for alcohol or drug abuse or dependence) significant cognitive impairment (for example learning disability or dementia) and active psychosis.
Outcomes
Primary Outcomes
Hospital Anxiety and depression Rating Scale- Depression subscale
Time Frame: Participants will be assessed at baseline and then end of therapy at 12 weeks
Measurement of depression
Secondary Outcomes
- Bradford Somatic Inventory(Participants will be assessed at baseline and then end of therapy at 12 weeks)
- Hospital Anxiety and Depression Scale, Anxiety subscale(Participants will be assessed at baseline and then end of therapy at 12 weeks)
- Brief disability questionnaire(Participants will be assessed at baseline and then end of therapy at 12 weeks)