A randomized clinical trial looking at disabling fatigue in multiple sclerosis occurs frequently. How should it be treated? A randomized clinical trial
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 90
Study Overview
Brief Summary
2013 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/23938046 protocol 2014 Results article in https://pubmed.ncbi.nlm.nih.gov/24850225 results 2015 Results article in https://pubmed.ncbi.nlm.nih.gov/25789625 results 2015 Results article in https://www.ncbi.nlm.nih.gov/pubmed/26358158 results (added 24/01/2019) 2017 Results article in https://www.ncbi.nlm.nih.gov/pubmed/28528566 results (added 24/01/2019) 2016 Results article in https://www.ncbi.nlm.nih.gov/pubmed/27233157 results (added 24/01/2019) 2014 Results article in https://www.ncbi.nlm.nih.gov/pubmed/24850225 results (added 24/01/2019) 2014 Results article in https://www.ncbi.nlm.nih.gov/pubmed/24677255 results (added 24/01/2019) 2016 Results article in https://www.ncbi.nlm.nih.gov/pubmed/26014607 results (added 24/01/2019) 2015 Results article in https://www.ncbi.nlm.nih.gov/pubmed/25789625 results (added 24/01/2019) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36621163/ Secondary analysis (added 10/01/2023)
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Diagnosis of MS according to the criteria of McDonald
- •2. Able to walk with no more than one unilateral walking aid i.e. able to walk with no more than one unilateral walking aid
- •3. Suffering from fatigue, defined as a score higher than 35 on the subscale fatigue of the Checklist Individual Strength (CIS)
- •4. Age between 18-70 years
Exclusion Criteria
- •1. Patients using in the last three months prior to inclusion Amantadine, Modafinil, Ritalin or Pemoline for their fatigue
- •2. Major depression