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临床试验/NCT06232850
NCT06232850已完成不适用

Examining the Relationship Between Wrist Position Sense and Manual Dexterity in Individuals With Multiple Sclerosis

Pamukkale University2 个研究点 分布在 2 个国家目标入组 48 人开始时间: 2024年1月11日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
48
试验地点
2
主要终点
Wrist Position Sense Assessment

研究概览

简要总结

No study has been found examining the effect of wrist position sense on manual dexterity in individuals with multiple sclerosis.The purpose of this study is to examine the effect of wrist position sense on manual dexterity of the hand.

详细描述

Multiple sclerosis is a chronic demyelinating disease of the central nervous system that occurs in young adults and usually progresses with attacks and remissions. As the disease progresses, symptoms such as fatigue, muscle weakness, loss of balance, loss of sensation, spasticity, visual disturbances and bladder dysfunction are observed. In addition to these symptoms, hand functions may be affected even in the early stages of the disease.

Appropriate motor control and mobility skills are required to perform manual dexterity effectively. Joint stabilization and perception of the joint's position and movement in space are needed for motor control of hand functions. In this process, position sense signals contribute significantly to the target localization and performance of the hand. Position sense signals must be constantly updated for the coordination and integration of hand position during manual activities such as holding or grasping an object. This is possible with a healthy sense of position.

Although it is known that position sense is affected in MS patients, no study has been found examining the effect of wrist position sense on manual dexterity. The purpose of this study is to examine the effect of wrist position sense on hand dexterity. Patients' manual dexterity will be evaluated using the Purdue Pegboard Test, and wrist position sense will be evaluated using the K-FORCE Sens® electrogoniometer.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patient group:
  • Disability score (EDSS: Expanded Disability Status Scale) should be between 0-
  • Being between the ages of 18-50
  • Not having had an attack in the last 3 months
  • Scoring 24 points or above on the Mini-Mental State Examination
  • Patients diagnosed with relapsing-remitting MS with a disease duration of at least 2 years
  • Patients without spasticity according to MAS
  • Control group:
  • Volunteers in a similar age range who agreed to participate in the study
  • Being between the ages of 18-50

排除标准

  • Patient group:
  • Presence of diagnosed visual impairment
  • Having other chronic diseases not related to MS
  • Having any orthopedic, neurological, rheumatological or metabolic diagnosis that causes upper extremity involvement
  • History of hand and upper extremity disorders, peripheral nerve disorders, and medical or psychiatric disorders that may significantly affect cognitive function
  • Presence of wrist joint range of motion limitation
  • Control group:
  • Having any orthopedic, neurological, rheumatological or metabolic diagnosis that causes upper extremity involvement
  • History of hand and upper extremity disorders, peripheral nerve disorders, and medical or psychiatric disorders that may significantly affect cognitive function
  • Presence of wrist joint range of motion limitation

结局指标

主要结局

Wrist Position Sense Assessment

时间窗: four mounth

Wrist position sense will be assessed with the KFORCE Sens® electrogoniometer. Target measurement values of 30° for wrist flexion, 30° for extension, 10° for radial deviation and 15° for ulnar deviation will be used.

次要结局

  • Purdue Pegboard Test (PPT)(four mounth)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

müge içelli

lecturer

Pamukkale University

研究点 (2)

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