The effects of 4 mg dexamethasone on swelling, analgesia, mouth opening and quality of life after surgical removal of lower third molar: A split-mouth triple-blind randomized placebo-controlled study

Phase 4

Completed

• Conditions: inflammation; Patients who required surgical removal of bilateral lower third molar; anti- the third molar surgery; dexamethasone

• Registration Number: TCTR20190503005
• Lead Sponsor: Research Institute, Rangsit University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-10-19
• Study Start: 2019-05-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

present with bilateral identical lower molar impaction according to Pell-Gregory classification (Pell & Gregory, 1933)

healthy patients who categorized in ASA I & ASA II (American Society for Anesthesiologists)

free from any systemic or local infection and have not taken anti-inflammatory drugs, steroids, or antibiotics within 2 weeks before the operation

Exclusion Criteria

pregnancy

lactating women

allergy or has an adverse effect from drugs that will be used in this study

patients who are unable to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Facial swelling and facial dimensions pre-operation, post-operative day 1, 3 and 7 mm/silk thread,Facial swelling and facial dimensions pre-operation, post-operative day 1, 3 and 7 mm/silk thread,Pain intensity Post-operative day 1, 2, 3 and 7 visual analog scale 1-10cm,Mouth opening Pre-operation, post-operative day1 , 3 and 7 mm/ digital calliper

Secondary Outcome Measures

Name	Time	Method
Quality of life Post-operative day 1, 3 and 7 scores/ 2 kinds of Health-related quality of life questionnaires (Modified OHIP, Modified OIDP)