Predicting tumor response to neoadjuvant chemotherapy in esophageal cancer patients-correlation between hypoxic imaging and signal transduction pathways
Not Applicable
- Conditions
- esophageal cancer
- Registration Number
- JPRN-UMIN000045299
- Lead Sponsor
- Institute of Advanced Clinical Medicine, Kindai University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Not received informed consent (2) Patient age less than 20 years old and more than 80 years old (3) Non-squamous cell carcinoma (4) Patient with synchronous cancer (5) Patient undergoing endoscopic mucosal resection (6) Patient undergoing chemoradiotherpy (7) Pregnant woman, lactating woman, possibility of pregnancy (8) Patient with serous complication affecting examination (9) inappropriate patient for this examination justified by attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We investigate the diagnostic accuracy of pretreatment FMISO PET/CT to histopathologic response and Positron Emission Tomography (PET) Response Criteria in Solid Tumors.
- Secondary Outcome Measures
Name Time Method (1)We investigate whether pretreatment FMISO PET/CT reflect tumor hypoxia or tumor immunity environment. (2)We investigate the relationship between pretreatment FMISO PET/CT and relapse-free survival (RFS).