Antistress effects of Cortex Mori Radicis extract via bidirectional phosphorylation in Korean healthy adults.

Not Applicable

Completed

• Conditions: Not Applicable

• Registration Number: KCT0001686
• Lead Sponsor: Seoul National University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 March 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

1. over 18 years old, healthy person
2. Able to communicate (excluding those who are illiterate or unable to fully understand the survey questions)
3. Understand investigational study, cooperative (willing to postpone previously scheduled for elective surgery) and able to participate until the end of the study.

Exclusion Criteria

1. Back Depression Inventory(BDI) = total score 24
2. Perceived Stress Scale-14(PSS-14) = total score 18
3. History of heart surgery and take medication that affect autonomic nervous system or heart function
4. Subject who has participated in another investigational study within 4 weeks prior to the first visit
5. body mass index >30kg/m2 or <18 kg/m2
6. having mental and physical problems or takes psychiatric drugs
7. Any condition that the principal investigator believes may put the subjects at undue risk

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Stress index of electroencephalography(EEG), Heart rate variability(HRV) and bio-signal

Secondary Outcome Measures

Name	Time	Method
saliva test(cortisol, Dehydroepiandrosterone, DHEA);blood test(cortisol, cytokine);beck depression inventory, state trait-anxiety scale-state,­ perceived stress scale-14,­ stress response inventory, ­pittsburgh sleep quality index, ­ fatigue severity scale, visual analogue scale;vital sign, body weight change, physical examination, blood test(complete blood count, liver function test, lipid etc.)