NCT05345314已完成不适用
Endoscopic Grading of Gastric Intestinal Metaplasia: a Validation Study in Korea
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 242
- 试验地点
- 1
- 主要终点
- Gastric intestinal metaplasia
研究概览
简要总结
Long-term Helicobacter pylori infection causes premalignant gastric conditions, such as atrophic gastritis and intestinal metaplasia. Image-enhanced endoscopy techniques such as narrow-band imaging (NBI) and magnifying endoscopy improve the diagnosis of gastric intestinal metaplasia (GIM). However, there are no comparative data on the utility of NBI and magnifying endoscopy for diagnosing GIM.
详细描述
This study aims to evaluate the diagnostic performance of NBI and magnifying endoscopy for GIM in a country with high risk of gastric premalignant lesions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Gastroscopy can be performed
- •Pathological analysis can be performed for analysis of gastric atrophy and intestinal metaplasia
排除标准
- •Age < 20 or > 80 years
- •Anemia (serum hemoglobin level < 10 g/dL)
- •Severe systemic disease
- •Advanced chronic liver disease
- •Use of certain medications, including proton pump inhibitors, H2-receptor antagonists, or antibiotics
- •History of H. pylori eradication
- •History of gastric surgery
- •Recent history of upper gastrointestinal bleeding
结局指标
主要结局
Gastric intestinal metaplasia
时间窗: 4 weeks
Gastric intestinal metaplasia would be assessed using pathological examination.
次要结局
- Degree of chronic gastritis(4 weeks)
研究者
Jun-Hyung Cho
Associate Professor
Soonchunhyang University Hospital
研究点 (1)
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