Effects of a cognitive-behavioural mindfulness intervention upon quality of life, depression and fatigue among multiple sclerosis (MS) patients

niversity Hospital Basel (Switzerland)0 个研究点目标入组 150 人开始时间: 2008年5月16日最近更新: 2019年7月1日

适应症

试验速览

•1. Both males and females, aged 18 - 70 years
•2. Verified diagnosis of MS with an expanded disability status scale score of less than or equal to 6.0 (from no disability to moderately severe disability MS) and no more than one step increase within the last year. We include patients with the followng types of disease:
•2.1. Relapsing-remitting MS and no more than two exacerbations within the last year, with at least three months since start of last relapse; or
•2.2. Secondary progressive disease
•3. Patients who have not initiated or changed treatment with a disease-modifying drug within the past three months
•4. Patients who have not been treated with corticosteroids within the previous 30 days
•5. Time since onset of disease will be evaluated and considered in statistical analyses but will not form a criterion for enrolment into the study

•1. Serious psychological disorders other than depression and anxiety syndromes, such as psychotic disorders, bipolar disorders, borderline personality disorders or active substance abuse disorders
•2. Evidence of dementia as indicated by testing below the fifth percentile in at least three of six dimensions of neuropsychological functioning (i.e. attention and concentration, processing speed, executive function, verbal memory, and verbal processing)
•3. Suicidality
•4. Other life-threatening or severely disabling physical disorders
•5. Current MS exacerbation
•6. Other disorders of the central nervous system (CNS) besides MS
•7. Symptomatic medication has been altered within the past three months
•8. Pregnancy
•9. Inability to understand written and spoken German

发起方

niversity Hospital Basel (Switzerland)