EUCTR2011-002775-42-AT进行中（未招募）不适用
Vienna Interventional Management of Stroke Study
Med. Uni. Wien, UK für Neurologie0 个研究点开始时间: 2012年11月22日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Age between 18 – 80 years
- •Clinical syndrome of a severe ischemic lesion within the anterior circulation („Total Anterior Circulation Syndrome TACS) or of basilar artery occlusion
- •NIHSS > 12
- •Start of IVT within 3 hours („bridging, „rescue) or within 4.5 hours (`primary endovascular management`)
- •Confirmation of proximal occlusion
- •Absence of exclusion criteria
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 120
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 120
排除标准
- •History of stroke within the last 3 months
- •History of subarachnoid or intracranial hemorrhage, known cerebrovascular arteriovenous malformation or CNS tumour
- •Clinical suggestion of subarachnoid hemorrhage and negative CT
- •Uncontrolled systolic blood pressure
- •Evidence of septic embolism etiologically related to stroke
- •Evidence of pericarditis including pericarditis after myocardial infarction
- •Operation or biopsy of a body organ within the last 30 days (not an exclusion criterion for primary endovascular treatment)
- •Trauma with inner or outer ulcerous wounds within the last 30 days (not an exclusion criterion for primary endovascular treatment)
- •Severe head trauma or concussion within the last 90 days
- •Current bleeding
- •Systemic bleeding (outside the head) within the last 30 days (not an exclusion criterion for primary endovascular treatment)
- •Known hereditary or acquired hemorrhagic diathesis , known hereditary or acquired coagulation factor deficiency; oral anticoagulation and a prolonged prothrombin time (INR > 1.5)
- •Women of childbearing age with known pregnancy or positive pregnancy test
- •Baseline platelet count < 100,000/mm or haematocrit < 25%
- •Patients on treatment with unfractioned heparin within the last 48 hours and prolonged partial thromboplastin time exceeding the upper limit of the local laboratory normal range
- •Arterial puncture at a non-compressible site or spinal tab within the past 7 days (not an exclusion criterion for primary endovascular treatment)
- •Uncertainty if neurological deficit is caused by vessel occlusion, e.g. after an epileptic seizure or neurologic/psychiatric illness
- •Known severe progressive or terminal illness
- •Any other reason that, in the opinion of the investigator, would bear a risk for rt-PA treatment
- •Imaging exclusion criteria:
- •CT-criteria:
- •any hemorrhage
- •edema with mass effect and midline shift
- •extensive hypodensity (> 1/3 of MCA territory)
- •MR-criteria:
- •Extensive diffusion lesion (> 1/3 of MCA territory)
- •No mismatch (at the discretion of treating neurologists/radiologists)
研究者
相似试验
招募中
不适用
The clinical intervention trial to post stroke depression and apathyPost stroke depression and apathyJPRN-UMIN000008312Yuaikai Hospital200
已完成
3 期
INTERVENTIONAL MANAGEMENT OF STROKE TRIAL CLINICAL PROTOCOL - IMS III A phase III, randomized, multi-center, open label, 900 subject clinical trial that will examine whether a combined intravenous (IV) and intra-arterial (IA) approach to recanalization is superior to standard IV rt-PA (Activase®/Actilyse®) alone when initiated within three hours of acute ischemic stroke onset.ischemic cerebrovascular accident1000796310014523StrokeNL-OMON36365ational Institute of Health20
进行中（未招募）
不适用
TERVENTIONAL MANAGEMENT OF STROKE TRIAL CLINICAL PROTOCOL (IMS III study)Ischemic StrokeMedDRA version: 14.0Level: PTClassification code 10065528Term: NIH stroke scale score increasedSystem Organ Class: 10022891 - InvestigationsMedDRA version: 14.0Level: LLTClassification code 10055221Term: Ischemic strokeSystem Organ Class: 10029205 - Nervous system disordersEUCTR2009-017454-12-DEniversity of Cincinnati - Academic Medical Center -Department of Neurology900
进行中（未招募）
不适用
INTERVENTIONAL MANAGEMENT OF STROKE TRIAL CLINICAL PROTOCOL(IMS III study)Ischemic StrokeMedDRA version: 14.1Level: PTClassification code 10065528Term: NIH stroke scale score increasedSystem Organ Class: 10022891 - InvestigationsMedDRA version: 14.1Level: LLTClassification code 10055221Term: Ischemic strokeSystem Organ Class: 10029205 - Nervous system disordersEUCTR2009-017454-12-NLniversity of Cincinnati - Academic Medical Center -Department of Neurology900
尚未招募
不适用
The significance of serum uric acid in acute stroke.CTRI/2021/08/035792DR SAKSHI