the Association of Psychological Distress in Patients With Advanced Lung Cancer Treated With Immunotherapy or Targeted Therapy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Objective response rate (ORR)
研究概览
简要总结
Psychological distress is a multi-factorial experience of a psychological, social, spiritual, and/or physical nature that may interfere with one's ability to cope effectively with cancer, physical symptoms and treatment. Psychological distress is common and affects the efficacy and prognosis of patients with lung cancer. The systematic anti-tumor therapy may effectively relieve psychological distress including anxiety, depression, and fatigue in patients with advanced lung cancer, the relief of the psychological distress can in turn improve the therapeutic effect.
In summary, this study is to explore the associations of (dynamic) psychological stress with the efficacy and survival of anti-tumor therapy including immunotherapy and targeted therapy for advanced lung cancer patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically proven diagnosis of lung cancer
- •18 years of age or older
- •Ability to understand and the willingness to sign a written informed consent document
排除标准
- •Not willing to participate in this clinical trial
结局指标
主要结局
Objective response rate (ORR)
时间窗: 20 years
Collect detailed clinical information on patients with SCLC via the electronic medical records
Disease control rate (DCR)
时间窗: 20 years
Collect detailed clinical information on patients with SCLC via the electronic medical records
Progression-free survival (PFS)
时间窗: 20 years
Collect detailed clinical information on patients with SCLC via the electronic medical records
次要结局
- Overall survival (OS)(20 years)
研究者
Xiaomin Niu
Principal Investigator
Shanghai Chest Hospital