the Association of Psychological Distress in Patients With Advanced Lung Cancer Treated With Immunotherapy or Targeted Therapy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lung Neoplasms
- Sponsor
- Shanghai Chest Hospital
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- Objective response rate (ORR)
- Status
- Recruiting
- Last Updated
- 11 months ago
Overview
Brief Summary
Psychological distress is a multi-factorial experience of a psychological, social, spiritual, and/or physical nature that may interfere with one's ability to cope effectively with cancer, physical symptoms and treatment. Psychological distress is common and affects the efficacy and prognosis of patients with lung cancer. The systematic anti-tumor therapy may effectively relieve psychological distress including anxiety, depression, and fatigue in patients with advanced lung cancer, the relief of the psychological distress can in turn improve the therapeutic effect.
In summary, this study is to explore the associations of (dynamic) psychological stress with the efficacy and survival of anti-tumor therapy including immunotherapy and targeted therapy for advanced lung cancer patients.
Investigators
Xiaomin Niu
Principal Investigator
Shanghai Chest Hospital
Eligibility Criteria
Inclusion Criteria
- •Histologically proven diagnosis of lung cancer
- •18 years of age or older
- •Ability to understand and the willingness to sign a written informed consent document
Exclusion Criteria
- •Not willing to participate in this clinical trial
Outcomes
Primary Outcomes
Objective response rate (ORR)
Time Frame: 20 years
Collect detailed clinical information on patients with SCLC via the electronic medical records
Disease control rate (DCR)
Time Frame: 20 years
Collect detailed clinical information on patients with SCLC via the electronic medical records
Progression-free survival (PFS)
Time Frame: 20 years
Collect detailed clinical information on patients with SCLC via the electronic medical records
Secondary Outcomes
- Overall survival (OS)(20 years)