Determination of Risk Factors for the Development of Obesity and Hypertension in Children According to Perinatal Programming of Metabolism

• Conditions: Metabolic Syndrome
• Interventions: Other: Risk Factors

• Registration Number: NCT04611412
• Lead Sponsor: Samarkand State Medical Institute

Brief Summary

to determine the risk factors for developing obesity in children with exogenous-constitutional obesity and arterial hypertension, according to the theories of early programming of metabolism

Detailed Description

A retrospective cohort study of 55 children aged 12 to 18 years (average 14.60±0.24 years) with exogenous-constitutional obesity was conducted, with 24 girls (43.6%) and 31 (56.4%) boys. Children were identified during dispensary examinations in family clinics in Samarkand in the period 2018-2019. All the examined children belonged to the Uzbek population.

Study Timeline

• Status Verified: 2020-10
• Study First Submitted: 2020-10-11
• Study First Submitted QC: 2020-10-26
• Last Update Submitted: 2020-10-26
• Study First Posted: 2020-11-02
• Last Update Posted: 2020-11-02
• Study Start: 2020-12-15
• Primary Completion: 2023-12-30
• Study Completion: 2024-01-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

• SDS (standart deviation score) of body mass index (BMI) ranging from +2.0 to +3.0

Exclusion Criteria

• secondary obesity and overweight genetic syndromes,
• refusal of the child and/or parents to be examined

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
1 group	Risk Factors	Group I consisted of 17 people (16.83%) with a uniform type of obesity
2 group	Risk Factors	Group II included 38 children with AO, and 20 of them had normal BLOOD pressure

Primary Outcome Measures

Name	Time	Method
Risk factors of metabolic syndrome	up to 36 months	A retrospective, cohort study of 55 children aged 12 to 18 years with exogenous constitutional obesity will be conducted Children with exogenous-constitutional obesity were divided by the presence of abdominal (visceral) obesity and the presence of hypertension.; Parents will be interviewed and medical records (forms 003/y and 112) of children with exogenous constitutional obesity will be analyzed. Also, on the basis of a specially developed questionnaire, children with exogenous constitutional obesity were surveyed. When conducting a survey of children and their parents, the following factors will be of particular importance: heredity, pregnancy, weight and body length at birth, the nature of nutrition in the first two years of life, eating habits, and physical activity.

Trial Locations

Locations (1)

Samarkand State Medical Institute; 🇺🇿 Samarkand, Uzbekistan