Antioxidants as cardioprotective therapy in aspirin resistant diabetes

Phase 1

• Conditions: Diabetes; Obesity; Cardiovascular; Cardiovascular - Coronary heart disease; Metabolic and Endocrine - Diabetes; Diet and Nutrition - Obesity

• Registration Number: ACTRN12615000293561
• Lead Sponsor: Griffith University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-03-27
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Group 1:
Normal healthy non smokers with no history of heart disease or bleeding disorder. Volunteers not on any special diet or medication. Health and food frequency questionnaire and baseline Full Blood Examination (all parameters within normal healthy population reference range) will be examined by a doctor (one of the investigators in our research team) to confirm health status.
Group 2:
Patient with diabetes but no history of heart disease, non smoker and with no other bleeding disorder or thrombosis and not on any other medication except diabetes treatment.
Group 3:
Patient with diabetes and previous history of heart disease, non smoker and with no other bleeding disorder or thrombosis and not on any other medication except diabetes treatment.
Group 4:
Pre-diabetes (sedentary people with BMI greater thnn 30 and atleast 2 other risk factors increasing chance of acquiring diabetes, non smoker and with no other bleeding disorder or thrombosis and not on any other medication except diabetes treatment.

Exclusion Criteria

1.Excessive bleeding tendency
2.Anti-Coagulant therapy
3.Recent GI bleed
4.Liver Disease
5.Anti-inflammatory Drugs affecting platelets
6.Platelet count of <125 & >450 X 1000 million/L of blood

Study & Design

• Study Type: Interventional
• Study Design: Not specified