A Randomised Trial of Peri-operative Nerve Block and Continuous Infusion of Local Anaesthetic Via Wound Catheter Versus Epidural in Patients Undergoing Open Liver Resection.

University of Edinburgh1 site in 1 country97 target enrollmentDecember 2012

Overview

The investigators plan to compare epidurals versus wound catheters for effects on pain relief and recovery following open liver surgery.

Registry

clinicaltrials.gov

Start Date

December 2012

End Date

August 2014

Last Updated

11 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Sponsor

Responsible Party

Sponsor

•Patients with contraindication to either epidural or wound catheter techniques.
•Inability to give written, informed consent.
•Jaundice (Bilirubin \> 100 μmol/L)
•Liver resection combined with secondary surgical procedure.
•Age \< 18 years
•Pregnant women
•patients on long term opiates for chronic pain

Length of stay

Time Frame: Measurement made on day of discharge which is expected to be on average bewteen 5 and 10 days after surgery.

Number of days (to nearest half day) patients stay in hospital.

Central Venous Pressure(During liver transection)
Molecular response to surgery(Days 0, 1 and 3)
Operative field asessment(During liver transection)
Estimated Blood Loss(Intra-operative)
Pain Scores(Performed daily at 0900 hours. On the day of surgery pain scores will be performed at 2, 6 and 12 hours post surgery.)
Pringle time(Intra-operative)