Effects of Motor Imagery and Action Observation on Gait Initiation and Spatiotemporal Gait Parameters in Multiple Sclerosis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change in Tibialis Anterior and Gastrocnemius Medialis Muscle Activity Amplitude
研究概览
简要总结
This study will investigate whether mentally simulating walking movements while watching others walk can improve walking performance in individuals with Multiple Sclerosis (MS). Participants will be divided into two groups: one group will watch walking videos and imagine themselves walking, while the other group will watch nature scenes. The study will measure muscle activity and walking patterns to assess the effects. The results may help support the use of mental practice techniques to improve mobility in people with MS.
详细描述
This study aims to explore the impact of mental simulation of walking movements on walking performance in individuals with Multiple Sclerosis (MS). The participants will be randomly assigned to two groups: the experimental group will watch walking-related videos and engage in mental imagery exercises, imagining themselves walking, while the control group will watch nature scenes without any walking-related content.
Objectives:
To determine whether mental imagery can enhance walking ability and gait parameters in individuals with MS.
To measure the effect of mental simulation on muscle activity and walking patterns, including stride length, walking speed, and balance.
Study Procedure:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
盲法说明
The study will be single-blinded. Participants will not be informed of their group assignment.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A confirmed diagnosis of multiple sclerosis (MS) by a neurologist
- •No history of relapse within the past 3 months and not currently experiencing a relapse
- •A score of 24 or higher on the standardized Mini Mental State Examination
排除标准
- •Presence of serious health conditions affecting the muscles, heart, lungs, or metabolism that could interfere with participation
- •History of other neurological disorders, head injury, or chronic psychiatric conditions
- •Chronic pain lasting longer than six months
- •Significant muscle stiffness in the legs that may affect EMG recordings
- •Hearing difficulties
- •Vision problems as determined by the Snellen visual acuity test
研究组 & 干预措施
Arm 1
Arm 1: Experimental Group: Action Observation + Motor Imagery
干预措施: Action Observation + Motor Imagery (Behavioral)
Arm 2
Arm 2: Control Group: Nature video
干预措施: Nature Video (Behavioral)
结局指标
主要结局
Change in Tibialis Anterior and Gastrocnemius Medialis Muscle Activity Amplitude
时间窗: Before and immediately after the intervention
Change in muscle activity amplitude (microvolts, µV) of tibialis anterior and gastrocnemius medialis during gait initiation measured by surface EMG.
Change in Tibialis Anterior and Gastrocnemius Medialis Muscle Activity Onset Latency
时间窗: Before and immediately after the intervention.
Change in onset latency (milliseconds, ms) of tibialis anterior and gastrocnemius medialis muscle activation during gait initiation measured by surface EMG.
Change in Step Length
时间窗: Before and immediately after the intervention
Change in step length (centimeters, cm) during gait initiation measured by the GAITRite system.
Change in Step Time
时间窗: Before and immediately after the intervention
Change in step time (seconds, s) during gait initiation measured by the GAITRite system.
Change in Step Width
时间窗: Before and immediately after the intervention
Change in step width (centimeters, cm) during gait initiation measured by the GAITRite system.
Change in Double Support Period
时间窗: Before and immediately after the intervention
Change in double support period (percentage of gait cycle, %) during gait initiation measured by the GAITRite system.
Change in Gait Velocity
时间窗: Before and immediately after the intervention
Change in gait velocity (centimeters per second, cm/s) during gait initiation measured by the GAITRite system.
Change in Cadence
时间窗: Before and immediately after the intervention
Change in cadence (steps per minute, steps/min) during gait initiation measured by the GAITRite system.
次要结局
- Motor Imagery Vividness(Baseline only)
- Mental Chronometry Ratio(Baseline only)
- Limb Laterality Recognition Performance(Baseline only)
- Cognitive Status(Baseline only)
- Anxiety and Depression(Baseline only)
- Fatigue Level(Baseline only)
- Visual Acuity(Baseline only)
- Disability Level(Baseline only)
研究者
Merve Ünal
Principal Investigator
Hacettepe University