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Clinical Trials/NCT05014282
NCT05014282
Active, not recruiting
Not Applicable

Randomized Trial of Automated Video-Assisted Smoking Treatment for People Living With HIV (Project RESOURCE)

H. Lee Moffitt Cancer Center and Research Institute1 site in 1 country638 target enrollmentDecember 15, 2021

Overview

Phase
Not Applicable
Intervention
Nicotine patch
Conditions
Smoking Cessation
Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Enrollment
638
Locations
1
Primary Endpoint
Self Reported 7 Day Abstinence Smoking Status
Status
Active, not recruiting
Last Updated
2 months ago

Overview

Brief Summary

This study will evaluate if Automated Treatment performs better, in terms of facilitating long-term smoking abstinence, than the more resource-intensive Standard Treatment.

Registry
clinicaltrials.gov
Start Date
December 15, 2021
End Date
September 23, 2026
Last Updated
2 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • smoked \>/=100 cigarettes in lifetime
  • English or Spanish speaking
  • Currently smoke \> 5 cigarettes/day
  • Willing to make a quit attempt within 1 week of enrollment
  • HIV positive
  • Process a smartphone compatible with the project app
  • Have a valid email address

Exclusion Criteria

  • Currently pregnant or breastfeeding
  • Current use of smoking cessation medications
  • Enrolled in a smoking cessation study
  • Household member enrolled in the study
  • Failure to electronically confirm participation within 14 days of randomization via electronic link sent to participant's smartphone

Arms & Interventions

Standard Treatment

Participants randomized to Standard Treatment (ST) will be provided with a 10-week supply of nicotine patches and lozenges. ST participants will be connected with their state's tobacco quitline services and will complete weekly 4-item smartphone assessments electronically for 26 weeks. The weekly assessments consist of questions on smoking status, motivation, self-efficacy, and perceived stress.

Intervention: Nicotine patch

Standard Treatment

Participants randomized to Standard Treatment (ST) will be provided with a 10-week supply of nicotine patches and lozenges. ST participants will be connected with their state's tobacco quitline services and will complete weekly 4-item smartphone assessments electronically for 26 weeks. The weekly assessments consist of questions on smoking status, motivation, self-efficacy, and perceived stress.

Intervention: Counseling

Standard Treatment

Participants randomized to Standard Treatment (ST) will be provided with a 10-week supply of nicotine patches and lozenges. ST participants will be connected with their state's tobacco quitline services and will complete weekly 4-item smartphone assessments electronically for 26 weeks. The weekly assessments consist of questions on smoking status, motivation, self-efficacy, and perceived stress.

Intervention: Nicotine lozenge

Automated Treatment

Participants randomized to Automated Treatment (AT) will be given a 10-week supply of nicotine patches and lozenges. AT will also comprise of: 1) 12 proactive treatment videos, delivered weekly, that are tailored on smoking status, motivation, agency, and/or negative affect/stress; 2) 26 weeks of on-demand access to treatment content; 3) 26 weeks of text content

Intervention: Nicotine patch

Automated Treatment

Participants randomized to Automated Treatment (AT) will be given a 10-week supply of nicotine patches and lozenges. AT will also comprise of: 1) 12 proactive treatment videos, delivered weekly, that are tailored on smoking status, motivation, agency, and/or negative affect/stress; 2) 26 weeks of on-demand access to treatment content; 3) 26 weeks of text content

Intervention: Nicotine lozenge

Automated Treatment

Participants randomized to Automated Treatment (AT) will be given a 10-week supply of nicotine patches and lozenges. AT will also comprise of: 1) 12 proactive treatment videos, delivered weekly, that are tailored on smoking status, motivation, agency, and/or negative affect/stress; 2) 26 weeks of on-demand access to treatment content; 3) 26 weeks of text content

Intervention: Smartphone-delivered automated treatment

Outcomes

Primary Outcomes

Self Reported 7 Day Abstinence Smoking Status

Time Frame: 12 Month Follow-Up

Participants will self report 7-day abstinence smoking status

Secondary Outcomes

  • Continuous Smoking Abstinence(12 Month Follow-Up)
  • Smoking Status by Saliva Cotinine Kit(12 Month Follow-Up)
  • Self Reported 24 Hours Smoking Abstinence(12 Month Follow-Up)
  • 30 Day Smoking Abstinence(12 Month Follow-Up)

Study Sites (1)

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